There will be over 50mm of rain in western and northern areas over the course of Thursday and Friday, according to Met Éireann.
The Orange warning – the second most serious that can be issued by Met Éireann – applies to Galway, Mayo, Clare, Cork, Kerry and Limerick.
Met Éireann said: “Southwesterly winds veering westerly will reach mean speeds 65 to 80km/h with gusts generally of 100 to 130km/h, higher in coastal regions.
"Storm surges will produce coastal flooding and damage."
The warning will take effect from 6pm tomorrow evening and apply until 3am on Friday morning.
Ahead of the storm hitting, the Department of Education and Skills has issued a statement for those with children attending school over the next two days.
"A status orange wind warning has been issued by Met Éireann for Galway, Mayo, Clare, Cork, Kerry and Limerick and will be in place from 6pm on Thursday to 3am on Friday morning," the online statement reads.
"Schools and all education centres (universities, IoTs and further education centres) in areas affected by a status orange alert should remain vigilant, and keep themselves appraised of any hourly and other updates from Met Éireann, and from their local authorities, local radio, and An Garda Síochána.
"In all events, and if in any doubt, schools and other education settings should err on the side of caution. Schools are empowered to make closure decisions if, in their judgment in the interests of the safety of the school community, it is prudent to do so.
"Any and all decisions about school closures will be informed by, as well as prevailing and predicted conditions, any damage that might have been caused to school buildings overnight or at any time during the storm, and whether such damage –where it exists – might present a risk to safety.
"Similarly, other education settings should make closure decisions based on those considerations."
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